Neuroprotective effect of paricalcitol in a rat model of transient global cerebral ischemia
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چکیده
منابع مشابه
P18: Neuroprotective Effect of Safranal, an Active Ingredient of Crocus Sativus, in a Rat Model of Transient Cerebral Ischemia
Safranal is a monoterpene aldehyde found in saffron (Crocus sativus L.) petals. It has been previously reported that safranal has a wide range of activities such as antioxidant and anti-inflammatory effects. In this study, we examined the effect of safranal on brain injuries in a transient model of focal cerebral ischemia. Transient focal cerebral ischemia was induced by middle cerebral artery ...
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Pervious studies have shown that pentoxifylline (PTX) has beneficial effects in reduction of stroke and brain trauma injuries in experimental animals. However, there is very little and controversial information about the effect of PTX on brain edema in cerebral ischemia. Therefore, the aim of this study was to determine the effects of different doses of PTX on brain edema and neurological m...
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Objective(s): Stroke poses a crucial risk for mortality and morbidity. Our study aimed to investigate the effect of p-coumaric acid on focal cerebral ischemia in rats. Material and Methods: Rats were randomly divided into four groups, namely Group I (control rats), Group II (ischemia rats), Group III (6 hr ischemia + p-coumaric acid rats) and Group IV (24 hr ischemia + p-coumaric acid rats). C...
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متن کاملNeuroprotective effect of low-dose lidocaine in a rat model of transient focal cerebral ischemia.
BACKGROUND A low concentration of lidocaine (10 microM) has been shown to reduce anoxic damage in vitro. The current study examined the effect of low-dose lidocaine on infarct size in rats when administered before transient focal cerebral isehemia. METHODS Male Wistar rats (weight, 280-340 g) were anesthetized with isoflurane, intubated, and mechanically ventilated. After surgical preparation...
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ژورنال
عنوان ژورنال: International Journal of Emergency Medicine
سال: 2020
ISSN: 1865-1372,1865-1380
DOI: 10.1186/s12245-020-00289-7